Role of platelets in immune system and inflammation
Ozge Sonmeza,, , Mehmet Sonmezb
a Istanbul University Cerrahpasa Medicine Faculty, English Medicine Programme, Istanbul, Turkey
b Karadeniz Technical University, School of Medicine, Department of Haematology, Trabzon, Turkey
Recebido 26 Janeiro 2017, Aceitaram 31 Maio 2017

Platelets have significant role in modulating clot formation. Additionally, emerging data indicates that platelets have considerable roles in inflammation and immune response. Platelets gather at the damaged cite and adhere to white blood cells. Subsequently, they release cytokines and chemokines which are chemotactic for neutrophils and monocytes. Therefore, platelets are necessary for targeting lymphocytes, neutrophils and monocytes to inflammation site. Those interactions enhance inflammation. Moreover, platelets serve as an immune cell by engulfing microbes. Presence of platelets affect prognosis in some bacterial or viral infection and several other diseases.

Platelets, Immune system

Open Access

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