Tuberculosis deaths in Northern Portugal. Predictors of mortality during TB treatment – A five-year analysis (2008–2012)
A.C.. Franco Spínolaa,, , M.. Camposb, A.. Rita Gaiob,c, A.. Maria Correiad, M.. Gomese, R.. Duartea,f,g
a Medical School of University of Porto, Porto, Portugal
b Science School of the University of Porto, Porto, Portugal
c Centre of Mathematics of the University of Porto, Porto, Portugal
d Public Health Department, Administra????o Regional de Sa??de do Norte, Porto, Portugal
e Occupational Health, Centro Hospitalar de Vila Nova de Gaia/Espinho, EPE, Vila Nova de Gaia, Portugal
f Hospital Centre of Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Portugal
g EpiUNIT Institute of Public Health Porto University, Porto, Portugal

The burden of tuberculosis in the Northern Region of Portugal remains high despite the implementation of risk group oriented strategies. Therefore characterization of the factors that relate to mortality among tuberculosis patients in this geographical region is relevant and explains the purpose of this study.

Records in the national surveillance system for tuberculosis characteristics for patients living in the North of Portugal and who completed tuberculosis treatment between 2008 and 2012 were studied by means of a retrospective case–control study design. Simple and multiple regressions were performed in order to assess the relationship between patient demographic, clinical and social history data with patient survival.

Male individuals over 45 years old with prior cancer (OR 4.63, 90% CI 2.66–8.04) and disseminated tuberculosis (OR 1.96, 90% CI 0.48–0.99) were identified as being those with the highest risk of death throughout tuberculosis treatment.

TB, Epidemiology, Predictors


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