Obstructive sleep apnea and diabetes mellitus
Jorge Valea,, , Paula Manuelb, Eurico Oliveirab, Ana Rita Oliveiraa, Eloisa Silvaa, Vitor Meloa, Marta Sousaa, João Carlos Alexandreb, Isabel Gila, Amparo Sancheza, Edite Nascimentob, António Simões Torresa
a Servi??o de Pneumologia do Centro Hospitalar Tondela-Viseu, Viseu, Portugal
b Servi??o de Medicina 1 do Centro Hospitalar Tondela-Viseu, Viseu, Portugal
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There is convincing evidence that obstructive sleep apnea (OSA) is highly associated with impaired glucose metabolism.


Analyze the prevalence of OSA in type 1 and type 2 diabetes mellitus (DM) patients. Evaluate the influence of OSA on glycemic control.


The adult patients with diabetes mellitus (DM) followed in the department of internal medicine were referred to our Sleep Unit. A home respiratory polygraphy was then performed on all patients with body mass index (BMI) < 40 kg/m2. The glycemic control was assessed by the value of glycated hemoglobin (Hba1c) in the previous 3 months.


A total of 46 patients were studied (20 men and 26 women), the mean age was 50 ± 15 years and mean BMI was 28.6 ± 4.9 kg/m2. The mean Hba1c was 8.3 ± 1.2. Twenty three patients had type 2 DM and 23 patients had type 1 DM. Twenty nine patients (63.0%) had OSA and 8.7% had severe OSA (AHI > 30/h). The mean CT90 was 5.3 ± 12.5 and the mean AHI was 13.6 ± 18.3. The mean AHI was similar between type 1 and type 2 DM (15.7 ± 24.5 Vs 11.6 ± 8.9; p = 0.46). The AHI was not correlated with the BMI. Type 2 DM patients with poor glycemic control (HbA1c > 7.5%) had a significantly higher mean AHI (14.3 ± 9.0 vs 6.4 ± 6.2; p = 0.038). This difference did not remain significant after adjustment for BMI (p = 0.151).


The prevalence of OSA in type 1 DM is similar to that found in type 2 DM. We note the high prevalence of OSA in younger patients with type 1 DM.

Obstructive sleep apnea syndrome, Diabetes mellitus, Glycemic control
Journal: Obstructive sleep apnea and diabetes mellitus

This article belongs to the Journal: Pulmonology


  • Impact Factor: 1.731(2017)
  • 5-years Impact Factor: 1,334
  • SCImago Journal Rank (SJR):0,342
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