Carcinoma Espinocelular da Língua – Factores de Risco e Importância do Reconhecimento de Lesões Pré-Malignas

Silva, Cátia Carvalho; Amaral, Barbas do; Bulhosa, José Frias;
Next Document Rev Port Estomatol Med Dent Cir Maxilofac.. 2010;51:49-55



To discuss the risk factors of squamous cell carcinoma of the tongue as well as emphasize the importance of systematic monitoring for early diagnosis of premalignant lesions.


Squamous cell carcinoma of the tongue as other oral malignancy is more common among males aged over 45 years-old; however, this gender rate tends to be less pronounced and more documented in young adults. The tongue presents itself as the preferentially place affected by this type of cancer, representing about 50% of oral carcinomas. Squamous cell carcinoma can be presented in different clinical aspect, like exophytic, endophytic, leukoplakia, erytroplakia or erytroleucoplakia. Patients should avoid exposure to major risk factors: tobacco and alcohol, but other factors may promote the emergence of potentially malignant lesions: viral infections, oral lichen planus, iron deficiency, immunosuppression, food ingestion in extreme temperatures and traumatic agents. Squamous cell carcinoma is often preceded by pre-malignant lesions, but mostly clinically detectable symptoms. These lesions appear to be in the form of leukoplakia, erytroplakia or eytroleucoplakia and whenever they are identified, a conventional biopsy should be performed to obtain a definitive histopathological diagnosis.

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Cátia Carvalho Silva, Barbas do Amaral, José Frias Bulhosa